The Center for Biomedical Studies (CBS) was created in 2003 to address the health disparities and enhance the quality of life in the lower Rio Grande Valley through research and educational programs that will bring long-term benefits to the state and the nation. The CBS encourages and fosters research and education in biomedicine, biotechnology, and bioinformatics. The scientific approaches are as varied as the interests of the individual researchers and range from fundamental studies of biological function to clinical trials. Translational and clinical research is performed in collaboration with associated hospitals and medical facilities. The CBS faculty educate undergraduate and graduate students in diverse biomedical-biotechnology fields and are developing the appropriate programs to achieve this goal. Community outreach and education is also part of the center’s mission. The majority of funding for CBS activities and programs has been supported by extramural funding from the National Institutes of Health ($15.2 million), Department of Defense ($1 million), private funding sources ($40,000), and institutional funds.